Effect of Dietary Patterns on Testosterone-Induced Prostatic Hyperplasia in Rats

This study investigated the influence of high-fat (beef and pork), high-sugar, and high-salt diets on testosterone-induced prostatic hyperplasia in a rat model. Thirty male rats were randomly assigned to different dietary groups and administered testosterone. The researchers measured serum PSA levels, prostate weight index, and conducted histopathological analysis. The findings showed that high-fat and high-sugar diets significantly increased prostate enlargement compared to the control group, while high-salt diet had no significant effect. These results suggest that dietary patterns play a crucial role in the development of benign prostatic hyperplasia, a common condition in elderly men. The study's limitations include the use of a rat model, and further research is needed to validate the findings in humans.