A Comprehensive Review on Botany, Ethnopharmacology, Phytochemistry, Biosynthesis, Pharmacology, Toxicity, Quality Control and Metabolomics of Coptidis Rhizome.
Uncover the secrets of Coptidis Rhizome, a traditional herbal remedy with a wealth of untapped potential. From its diverse phytochemistry to its broad pharmacological impacts, this comprehensive review illuminates a path forward for harnessing its power in modern medicine.
This review delves into the multifaceted aspects of Coptidis Rhizome (CR), a renowned traditional Chinese herbal remedy. It explores the plant's botany, ethnopharmacology, phytochemistry, biosynthesis, pharmacology, toxicology, quality control, and metabolomics. Over 200 compounds have been identified in CR, with alkaloids being the most abundant and bioactive constituents. CR and its active ingredients exhibit a wide range of therapeutic effects, including anti-inflammatory, anticancer, hypoglycemic, and cardiovascular benefits. The review highlights the significant progress made in CR research, providing a solid foundation for its continued development and utilization in modern medicine. However, the review also acknowledges the need for further investigation to fully harness the potential of this remarkable herbal resource.