Exploring the medicinal potential of Alnus japonica: a comprehensive review of phytochemicals and therapeutic applications.
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Journal:
Naunyn-Schmiedeberg's archives of pharmacology
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Published:
September 04, 2025
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Authors:
['Khalil AAK', 'Bae H.']
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Category:
Oncology
Discover the hidden healing powers of the Alnus japonica tree - a natural treasure trove of potent phytochemicals with promising therapeutic applications, from cancer prevention to liver protection.
This comprehensive review explores the medicinal potential of Alnus japonica, a tree native to East Asia. Through an in-depth analysis of its chemical composition, the study uncovers a rich array of bioactive compounds, including diarylheptanoids, flavonoids, tannins, and phenolic acids. These compounds have demonstrated a wide range of therapeutic activities, such as anticancer, antioxidant, anti-inflammatory, hepatoprotective, and lipid-regulating properties. The review highlights the underlying mechanisms by which these phytochemicals modulate key cellular pathways, particularly those involved in oxidative stress and immune response. While the findings suggest the immense medicinal potential of Alnus japonica, further research is needed to fully harness its therapeutic applications and overcome any limitations.