Advancements in the Applications of Mono and Bimetallic Rhenium(I) Complexes in Anticancer Therapeutics, Bioimaging, and Biosensing.
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Journal:
Chemistry, an Asian journal
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Published:
July 28, 2025
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Authors:
['T N', 'R B', 'S K AK', 'Paira P.']
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Category:
Oncology
Discover the revolutionary potential of rhenium(I) complexes in cancer treatment, bioimaging, and biosensing. These versatile compounds offer unparalleled capabilities, from targeting specific cellular organelles to detecting a wide range of biomolecules, transforming the futu...
This comprehensive review explores the advancements in rhenium(I) complexes and their diverse applications. The researchers investigated monometallic, bimetallic, and heteroobimetallic complexes, evaluating their efficacy as anticancer agents, their ability to target specific cellular organelles for live-cell imaging, and their potential as biosensors for detecting substances like nitric oxide, proteins, and various ions. The unique physical and chemical properties of these complexes, including their luminescence, lipophilicity, and cytotoxicity, can be tailored by modifying the ligands. This review provides a thorough examination of the current and future challenges and opportunities in the field, paving the way for groundbreaking developments in cancer treatment, bioimaging, and biosensing.